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DOE handbook
1.0 INTRODUCTION
2.0 FRAMEWORK FOR DEVELOPMENT AND APPLICATION OF TEELS
2.1 Planning for Chemical Emergencies
2.2 Exposure Assessment and Risk Assessment
2.3 Need for TEEL Values
2.4 Protective Action Criteria and Risk Management
2.5 Populations at Risk
2.6 Nature and Severity of Toxic Effects
2.7 Exposure to Known, Probable, and Possible Carcinogenic Chemicals
2.8 Comparison of AEGLs, ERPGs, and TEELs
2.9 SCAPA and the TEEL Advisory Group
3.0 TEEL DEVELOPMENT METHODOLOGY
3.1 General Considerations
3.2 Concentration Limit-Based TEELs
3.2.1 Sources of Data
3.2.2 Particles not Otherwise Specified
3.2.3 Concentration or Dose Dependent Toxicity of Chemicals
3.2.4 Order of Consideration
3.3 Special Considerations
3.3.1 Simple Asphyxiants
3.3.2 Radioactive Compounds
3.3.3 Compound-to-Element Molecular Weight Ratio Adjustments
3.4 Toxicity-Based TEELs
3.4.1 Types of Data
3.4.2 Sources of Data
3.4.3 Deriving TEELs from Toxicity Parameters
3.5 TEELs when Exposure Limits and Toxicity Parameters are Missing
3.5.1 DOE Policy Mandate
3.5.2 TEELs Derived from Structure-Activity Relationships
3.5.3 TEELs Derived from Health Hazard Ratings
3.5.4 TEELs Derived from TEELs for Other Levels
3.6 Default Criteria
3.7 Adjustments
3.7.1 Toxicity-Based to Concentration-Based Ratio Adjustments
3.7.2 TEEL-3 ≤ 500 mg/m3 for Aerosols
3.7.3 Rounding Guidelines for Final TEELs
3.8 Other Considerations
3.8.1 Lower Explosive Limits
4.0 SAMPLE TEEL CALCULATIONS
4.1 Chemicals with AEGLs
4.2 Chemicals with ERPGs, but No AEGLs
4.3 Chemicals with Concentration Limits, but No Toxicity Data
4.3.1 Straightforward Example: MAPP Gas, CAS RN 59355-75-8
4.3.2 Requiring Calculation: Lead Bromide, CAS RN 10031-22-8
4.4 Chemicals with both Concentration Limit and Toxicity Data
4.5 Chemicals with Toxicity Data, but No Concentration Limits
4.6 Chemicals with neither Concentration Limits nor Toxicity Data
4.6.1 Solids and Nonvolatile Liquids: Europium, CAS RN 7440-53-1
4.6.2 Volatile Liquids and Gases: Carbon Trifluoride, CAS RN 75-46-7
4.6.3 Structure Activity Relationships: Bismuth Hydroxide, CAS RN 10361-43-0
4.7 Simple Asphyxiants
5.0 REVIEW PROCESS AND PUBLICATION
5.1 Quality Control and Quality Assurance
5.1.1 Sources
5.2 TEEL Methodology Review
5.2.1 DOE: SCAPA
5.2.2 Peer-Reviewed Publications
5.3 Software Quality Assurance
5.4 Publication of Protective Action Criteria Values
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